Lambert-Eaton Myasthenic Syndrome (LES)

Lambert–Eaton myasthenic syndrome From Wikipedia, the free encyclopedia   (Redirected from  Lambert-Eaton myasthenic syndrome ) Lambert–Eaton myasthenic syndrome Classification and external resources Neuromuscular junction. Lambert–Eaton myasthenic syndrome is caused by autoantibodies to the presynaptic membrane. Myasthenia gravis is caused by autoantibodies to the postsynaptic acetylcholine receptors. 1.  Presynaptic  terminal 2.  Sarcolemma 3.  Synaptic vesicle 4.  Nicotinic acetylcholine receptor 5.  Mitochondrion ICD - 10 G 73.1 ICD - 9 358.1 DiseasesDB 4030 MedlinePlus 000710 MeSH D015624 Lambert–Eaton myasthenic syndrome  ( LEMS , also  Lambert–Eaton syndrome , or  Eaton–Lambert syndrome ) is a rare  autoimmune  disorder that is characterized by  muscle weakness  of the limbs. It is the result of an  autoimmune reaction  in which  antibodies  are formed against presynaptic  voltage-gated calcium channels , and likely other nerve terminal proteins, in the